Scireq flexiVENT for advanced respiratory mechanics

flexiVENT - system for advanced respiratory mechanics

flexiVENT for advanced respiratory mechanics

flexiVent (Scireq Inc) is an integrated platform combining computer-controlled ventilator with data acquisition & analysis for detailed measurement of respiratory mechanics in subjects from under 10g to over 45kg.

During ventilation, the movement of the precision pump and the opening/closing of air valves are precisely co-ordinated.

Respiratory mechanics are calculated from the data collected during a "perturbation" (a highly specific oscillatory flow or volume waveform).

features

• highly modular design makes it easy to adapt the standard system to subjects of different sizes and for specialized applications
• full control from easy-to-use software (Windows)

options

• computer-controlled nebulizer for inhaled challenges, and rapid generation of dose-response curves
• vital signs monitoring and computer control of external devices
• glp software extension

other applications

thoracic imaging

• gating signal to a preclinical imaging scanner makes resolution and signal-to-noise ratio (SNR) of thoracic images more resistant to movement artefacts
• custom solutions for MRI scans with hyperpolarized contrast gas
• integration kits for SkyScan 1076 and other micro-CT scanners

total liquid ventilation

• ventilation of the lungs with perfluorocarbons (PFCs) offers exciting new possibilities for investigation of lung function
• setup (PFC-filled cylinders, condensation unit, precision transducers) integrates fully with the standard flexiVent system

isolated airway mechanics

• study of isolated airway segments